DIFFERENCES IN BLOOD BIOCHEMICAL PARAMETERS IN PHARMACORESISTANT AND NON-PHARMACORESISTANT EPILEPSY.

Abstract

Annotation: Epilepsy is a chronic neurological disorder characterized by recurrent seizures and significant metabolic disturbances. One of the major challenges in epilepsy treatment is pharmacoresistant epilepsy, where seizures persist despite appropriate antiepileptic drug therapy. This condition is associated not only with neuronal dysfunction but also with systemic metabolic changes. The present article analyzes differences in blood biochemical parameters between pharmacoresistant and non-pharmacoresistant epilepsy patients. The focus is placed on liver enzymes, lipid profile, glucose metabolism, inflammatory markers, electrolyte balance, and oxidative stress indicators.