METABOLIC IMPACT OF SLEEVE GASTRECTOMY WITH BIPARTITION IN PATIENTS WITH OBESITY

Abstract

Annotation: Sleeve gastrectomy with bipartition is a novel bariatric surgical technique that combines restrictive and malabsorptive components to treat morbid obesity. This annotation explores the metabolic outcomes of this procedure, particularly its effects on glycemic control, insulin sensitivity, lipid profile, and weight loss sustainability in obese patients. The surgery involves a longitudinal gastric resection (sleeve) followed by a small intestinal diversion (bipartition), which alters nutrient flow and hormonal response. Clinical studies have shown that this method not only promotes significant weight reduction but also leads to marked improvements in type 2 diabetes mellitus, often achieving remission independently of weight loss. Additionally, it has demonstrated favorable impacts on lipid metabolism, blood pressure regulation, and inflammatory markers. Compared to traditional Roux-en-Y gastric bypass or sleeve gastrectomy alone, sleeve gastrectomy with bipartition may offer superior metabolic benefits with fewer nutritional deficiencies. This annotation highlights the importance of long-term follow-up and individualized patient selection to optimize outcomes and minimize complications.