ADVANCES IN MEDICAL CHEMISTRY: MOLECULAR MECHANISMS, DIAGNOSTIC APPLICATIONS, AND THERAPEUTIC DEVELOPMENT

Abstract

Medical chemistry plays a fundamental role in understanding biological processes at the molecular level and creating modern diagnostic and therapeutic agents. Advances in structural chemistry, molecular modeling, and biomolecular interaction studies have led to the development of highly selective drugs, biomarkers, and biocompatible materials. This article reviews key aspects of medical chemistry, including the physicochemical properties of biomolecules, enzyme–substrate interactions, drug design strategies, pharmacokinetics, and targeted therapy. The article also highlights recent progress in nanotechnology-based drug delivery and discusses challenges associated with drug resistance and toxicity.