SCLEROPOLYKYSTIC OVARIAN DISEASE

Abstract

Scleropolykystic ovarian disease (SPOD), more commonly referred to as polycystic ovary syndrome with stromal sclerosis, is a complex endocrine and metabolic disorder affecting women of reproductive age. The condition is characterized by ovarian morphological changes, hyperandrogenism, ovulatory dysfunction, and metabolic disturbances. SPOD represents a more advanced morphological form of polycystic ovary syndrome (PCOS), distinguished by dense ovarian stroma and fibrotic changes that impair follicular maturation. This article analyzes the pathophysiology, clinical manifestations, diagnostic criteria, and current management approaches of scleropolykystic ovarian disease, emphasizing its reproductive and metabolic consequences. Based on literature analysis, the paper highlights the importance of early diagnosis and multidisciplinary management to improve fertility outcomes and reduce long-term health risks.