RIVOJLANISHNING DASTLABKI DAVRIDAGI OQ ZOTSIZ KALAMUSHLARDA PAST KONSENTRATSIYADAGI SIRKA KISLOTASI TA’SIRIDA JIGARNING MORFOLOGIK O‘ZGARISHLARI
Keywords:
oq zotsiz kalamush, sirka kislotasi, jigar, gistologiya, gepatotsit, morfologik o‘zgarishlar, gepatotoksik.Abstract
Ushbu maqolada tajribadan so‘ng kuzatilgan natijalariga ko‘ra, 6% li sirka kislotasi yuborilgan va biokorreksiya qilinmagan oq zotsiz kalamushlarning jigar parenximasida sezilarli morfologik o‘zgarishlar kuzatildi. Gistologik kuzatuvlarda gepatotsitlarning kichrayishi, yadro-sitoplazma nisbatining ortishi, sitoplazmada vakuolizatsiya, markaziy venalarda venoz staz, bo‘laklararo qon tomirlarining kengayishi, sinusoidlarning deformatsiyasi hamda biliar epiteliyda proliferativ-displastik jarayonlar aniqlangan. Umuman olganda, 1 oy davomida jigar to‘qimalarida distrofik, yallig‘lanishli va kompensator o‘zgarishlar birgalikda kechdi. Ushbu topilmalar sirka kislotasining gepatotoksik ta’sirga ega ekanligini hamda yosh organizmlarda jigar hujayralarining ushbu ta’sirga sezgirligini ko‘rsatadi.
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