MIKROELEMENTOZNING QALQONSIMON BEZ MORFO-FUNKSIONAL XOLATIGA TAʼSIRI
Keywords:
Kalit so‘zlar: qalqonsimon bez, mikroelementoz, yod, selen, temir, og‘ir metallar, oksidativ stress, morfo-funksional o‘zgarishlar.Abstract
Annotatsiya: Ushbu tezisda mikroelementlarning qalqonsimon bez morfo-funksional holatiga ta’siri ko‘rib chiqiladi. Yod, selen va temir gormon biosintezi hamda antioksidant himoyada muhim rol o‘ynaydi; ularning yetishmovchiligi yoki ortiqchaligi struma, gipotiroidizm va autoimmun jarayonlarga sabab bo‘lishi mumkin. Rux, mis va boshqa mikroelementlar hujayra proliferatsiyasi va gen ifodalanishida ahamiyatli. Og‘ir metallar (Cd, Pb, Hg) tirotsitlarda oksidativ stress va degenerativ o‘zgarishlarni kuchaytiradi. Qalqonsimon bez patologiyalarini oldini olishda mikroelement monitoringi va oqilona profilaktika strategiyalari muhimdir.
References
1. Bryliński Ł. et al. Effects of trace elements on endocrine function and pathogenesis of thyroid diseases—a literature review //Nutrients. – 2025. – Т. 17. – №. 3. – С. 398.
2. Köhrle J. Selenium, iodine and iron–essential trace elements for thyroid hormone synthesis and metabolism //International journal of molecular sciences. – 2023. – Т. 24. – №. 4. – С. 3393.
3. Rostami R. et al. Association Between Essential Trace Elements and Thyroid Antibodies in the Blood of Women with Newly Diagnosed Hashimoto’s Thyroiditis //International Journal of Endocrinology and Metabolism. – 2024. – Т. 22. – №. 2. – С. e145599.
4. Zhou Q. et al. Trace elements and the thyroid //Frontiers in endocrinology. – 2022. – Т. 13. – С. 904889.
