VARIKOSELENING ETIOLOGIYASI, PATOGENEZI, KLINIK BELGILARI, DIAGNOSTIKASI VA DAVOLASH USULLARI
Keywords:
Varikosele, moyak venalari, plexus pampiniformis, erkak bepushtligi, spermatogenez, venoz refluks, venoz klapan yetishmovchiligi, moyak harorati, oksidativ stress, gipoksiya, spermogramma, urologiya, andrologiya, Doppler ultratovush tekshiruvi, Valsalva sinamasi, mikrojarrohlik, Marmar operatsiyasi, laparoskopik varikoselektomiya, reproduktiv salomatlik, fertilitetAbstract
Varikosele — erkaklar reproduktiv tizimida keng tarqalgan kasallik bo‘lib, moyak venalarining patologik kengayishi bilan tavsiflanadi. Ushbu kasallik erkak bepushtligining eng ko‘p uchraydigan sabablaridan biri hisoblanadi. Zamonaviy urologiya va andrologiyada varikosele muammosi muhim klinik va ijtimoiy ahamiyatga ega.
Varikosele ko‘pincha o‘smirlik va yoshlik davrida rivojlanadi hamda uzoq vaqt davomida klinik belgilarsiz kechishi mumkin. Kasallik o‘z vaqtida aniqlanmasa, spermatogenez buzilishi, moyak atrofiyasi va erkak jinsiy funksiyasining pasayishiga olib keladi. Shu sababli varikoseleni erta tashxislash va davolash zamonaviy tibbiyotning dolzarb vazifalaridan biridir.
References
1. World Health Organization. The influence of varicocele on male fertility. WHO Press, Geneva, 2019.
2. Marmar J. L., Agarwal A., Prabakaran S. Reassessing the value of varicocelectomy as a treatment for male infertility. Fertility and Sterility, 2017.
3. Goldstein M. Surgical management of male infertility. Cambridge University Press, 2018.
4. Naughton C. K., Nangia A. K., Agarwal A. Varicocele and male infertility: Part I – Pathophysiology. Human Reproduction Update, 2016.
5. Esteves S. C., Miyaoka R., Agarwal A. An update on the clinical assessment of the infertile male. Clinics, 2017.
6. Practice Committee of the American Society for Reproductive Medicine. Report on varicocele and infertility. Fertility and Sterility, 2020.
7. Damsgaard J., Joensen U. N. Varicocele as a cause of male infertility. Nature Reviews Urology, 2019.
8. Sharlip I. D., Jarow J. P., Belker A. M. Best practice policies for male infertility. Journal of Urology, 2018.
9. Agarwal A., Deepinder F., Cocuzza M. Efficacy of varicocelectomy in improving semen parameters. Asian Journal of Andrology, 2016.
10. WHO Manual. Laboratory manual for the examination and processing of human semen. 6th edition, 2021.
