THE EFFECT OF HYALURONIC ACID COMPOUNDS IN THE COMPLEX TREATMENT OF GENERALISED PERIODONTITIS: A SYSTEMATIC REVIEW OF SCIENTIFIC LITERATURE
Keywords:
Hyaluronic acid has anti-inflammatory and antibacterial characteristics and is crucial to the wound healing process. It participates in several biological processes, such as cell motility, adhesion, and phagocytosis (10). Commercial preparations including high molecular weight non-toxic hyaluronic acid (1.5 * 10^5) have been used as adjuncts to both non-surgical and surgical periodontal treatment (11). Due to its sticky nature, GK is presumed to persist in the tissues where it executes its biological tasks (11).Abstract
Gingivitis and periodontitis, together referred to as periodontal disorders, are chronic infections of the periodontal tissues linked to biofilms (1,3). Globally, 20 to 50 percent of individuals are afflicted by periodontal diseases, with severe periodontitis being a primary contributor to tooth loss. Surgical and conservative methods are used to treat gingivitis and periodontitis (5,6).
A considerable array of adjuvant drugs has been suggested to enhance the clinical trajectory after primary therapy, used alongside primary therapeutic strategies (7). These adjuvants include diverse anti-inflammatory, antibacterial, and antiseptic agents, including chlorhexidine and essential oils. Additional chemicals that facilitate tissue regeneration and healing include hyaluronic acid (HA) and enamel matrix proteins.
References
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