ВЛИЯНИЕ НАСЛЕДСТВЕННОЙ ОТЯГОЩЁННОСТИ РАССТРОЙСТВАМИ ШИЗОФРЕНИЧЕСКОГО СПЕКТРА НА КЛИНИЧЕСКУЮ КАРТИНУ ШИЗОФРЕНИИ
Keywords:
шизофрения, наследственная отягощённость, депрессия, дебют шизофрении.Abstract
выявление особенностей клинического дебюта шизофрении, а также клинических аспектов, связанных с наследственной отягощённостью в рамках расстройств шизофренического спектра.
References
1. Bleuler E. Dementia praecox or the group of schizophrenias. New York: International Universities Press.; 1950.
2. Fusar-Poli P, Politi P. Paul Eugen Bleuler and the birth of schizophrenia (1908). Am J Psychiatry. 2008;165(11):1407. https://doi.org/10.1176/appi.ajp.2008.08050714
3. Janoutová J, Janácková P, Serý O, Zeman T, Ambroz P, et al. Epidemiology and risk factors of schizophrenia. Neuro Endocrinol Lett. 2016;37(1):1-8. PMID: 26994378.
4. Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry. 2003;60(12):1187-1192. https://doi.org/10.1001/archpsyc.60.12.1187
5. Eyles Dw. How do established developmental risk-factors for schizophrenia change the way the brain develops? Transl Psychiatry. 2021;11(1):158. https://doi.org/10.1038/s41398-021-01273-2
6. Mortensen PB, Pedersen MG, Pedersen CB. Psychiatric family history and schizophrenia risk in Denmark: which mental disorders are relevant? Psychol Med. 2010;40(2):201-210. https://doi.org/10.1017/S0033291709990419 7. Mortensen PB, Pedersen CB, westergaard T, wohlfahrt J, Ewald H, et al. Effects of family history and place and season of birth on the risk of schizophrenia. N Engl J Med.
1999;340(8):603-608. https://doi.org/10.1056/NEJM199902253400803
8. Kowalec K, Lu Y, Sariaslan A, Song J, Ploner A, et al. Increased schizophrenia family history burden and reduced premorbid Iq in treatment-resistant schizophrenia: a Swedish National Register and Genomic Study. Mol Psychiatry. 2021;26(8):4487-4495. https://doi.org/10.1038/s41380-019-0575-1
9. Esterberg ML, Trotman HD, Holtzman C, Compton MT, walker EF. The impact of a family history of psychosis on ageat-onset and positive and negative symptoms of schizophrenia: a meta-analysis. Schizophr Res. 2010;120(1-3):121-130. https://doi.org/10.1016/j.schres.2010.01.011
10. Käkelä J, Panula J, Oinas E, Hirvonen N, Jääskeläinen E, Miettunen J. Family history of psychosis and social, occupational and global outcome in schizophrenia: a meta-analysis. Acta Psychiatr Scand. 2014;130(4):269-278. https://doi.org/10.1111/acps.12317
11. Ran MS, xiao Y, Zhao x, Zhang TM, Yu YH, et al. Family history of psychosis and outcome of people with schizophrenia in rural China: 14-year follow-up study. Asian J Psychiatr. 2018;32:14-19. https://doi.org/10.1016/j.ajp.2017.11.016
12. Sullivan PF, Magnusson C, Reichenberg A, Boman M, Dalman C, et al. Family history of schizophrenia and bipolar disorder as risk factors for autism. Arch Gen Psychiatry.
2012;69(11):1099-1103. https://doi.org/10.1001/archgenpsychiatry.2012.730
13. Benros ME, Pedersen MG, Rasmussen H, Eaton ww, Nordentoft M, Mortensen PB. A nationwide study on the risk of autoimmune diseases in individuals with a personal or a family history of schizophrenia and related psychosis. Am J Psychiatry. 2014;171(2):218-226. https://doi.org/10.1176/appi.ajp.2013.13010086
14. Power RA, Verweij KJ, Zuhair M, Montgomery Gw, Henders AK, et al. Genetic predisposition to schizophrenia associated with increased use of cannabis. Mol Psychiatry. 2014;19(11):1201-1204. https://doi.org/10.1038/mp.2014.51
