USE OF ANTIPROTOZOAL THERAPY IN HIV INFECTION WITH INTESTINAL PARASITOSIS
Keywords:
parasitic invasion, HIV infection, antiprotozoal therapy, ARTAbstract
Intestinal parasites and helminths cause immunodeficiency in the human body, which directly aggravates the course of the disease in HIV-infected people. The purpose of the study: to study the effect of parasitotherapy on the course of the disease when HIV infection is accompanied by intestinal parasites. Research materials and methods. 70 patients undergoing treatment for HIV infection were examined. General clinical, IFA, PCR, coproovoscopy and formalin sedimentation methods were used for the research.
References
1. Abdiev T. A., Egamberdiev O. A., Abdiev F. T., Saidakhmedova D. B., Abdusattarov M. M., Vakhobov T. A., Kovalenko D. A., Makhmudova L. B. Clinical management of helminthiasis. - Tashkent, - 2013.
2. Abdiev T. A., Saidakhmedova D. B., Suvonkulov U. T., Akhmedova M. D., Saipov F. S., Makhmudova L. B., Abdiev F. T., Vakhobov T. A., Kovalenko D. A., Kachugina L. V., Anvarov J. A. Parasitic diseases of humans in Uzbekistan. - Tashkent, 2018.
3. Achilova M.M., Bayjanov A.K., Khikmatullaeva A.S., Kuchkarova N.M. Clinical course of HIV infection with intestinal parasitosis and allergodermatosis / Asian journal of Pharmaceutical and biological research AJPBR, 2023. - Volume 12. - Issue 2. - P. 203-207.
4. Baijanov A.K., Achilova M.M., Yarmukhamedova N.A. The influence of intestinal giardiasis on the hepatobiliary system and HIV-infected patients // IV International scientific and practical conference "Science and education in the modern society: actual questions and innovative research". - Penza, 2021. - S. 129-131.
5. Bayjanov A.K., Achilova M.M., Khikmatullaeva A.S., Ibadullaeva N.S. Relationship of incidence of intestinal parasitosis with the level of immunodeficiency in patients with HIV infection / Asian journal of Pharmaceutical and biological research AJPBR, 2023. - Volume 12. - Issue 2. - P. 152-157.
6. Bayjanov A.K., Achilova M.M., Ibadova N.X. The frequency of comorbid and opportunistic pathologies in patients with HIV infection // International scientific and practical conference «Cutting-edge science». - Shawnee, 2023. - Р. 8-10.
7. Djuraeva K. S. i dr. Klinichesko-epidemiologicheskie osobennosti chronicheskogo brucelleza u genshchin fertilnogo vozrasta po materialam OIKB goroda. - 2022.
8. Kesserling A. M. Risk factors for treatment-limiting toxicities in patients starting nevirap me-containing antiretroviral therapy // AIDS. - 2009. - Vol. 23. - P. 1689-1699.
9. Kozlov S. S., Sergiev V. P., Lobzin Yu. V. Parasitic diseases of humans. Protozoosis and helminthosis. Publisher: Foliant (med), 2016. 639 p.
10. Lysenko A. Ya., Vladimova M. G., Kondrashin A. W., Maiori D. J. Clinical parasitology. - Geneva. - WHO. - 2003.
11. Mazus A. I., Kaminsky G. D., Zimina V. N. i dr. National clinical recommendations for diagnosis and treatment of adult HIV infection. M.; 2013.Нестеров А. С. Особенности патогенеза и терапии хронических дерматозов при бластоцистной инвазии. дис. д.м.н / Ульяновск, 2009.
12. Pokrovsky V. V. HIV infection and AIDS: clinical recommendations. 2-e izd. M.: GEOTAR-Media; 2010.
13. Pokrovsky V. V. HIV-infection and SPID (National leadership). - 2013. - S. 608.
14. Prikaz №81 Ministry of Health of the Republic of Uzbekistan "On the implementation of national clinical protocols for HIV infection" dated 03/04/2015.
15. Saag M. S., Chambers H. F., Eliopoulos G. M., Gilbert D. N. The Sanford guide to HIV/AIDS therapy 2012. - Sperryville, VA, USA: Antimicrobial Therapy Inc., - 2012. – Р. 214.
16. Solomay T. V. Human blastocystosis: horse mechanism vzaimodeystvya parasite s organism host k clinical manifestation // Sanitarnyy vrach. - 2018. - No. 8. – C. 35-42
17. Tozzi V. Pharmacogenetics of antiretrovirals. Antiviral Res. 2010, Jan; 85 (1): р. 190-200.
18. Uspensky A. V., Malakhova E. I., Ershova T. A. Sovremennaya situatsiya po parazitozam i mery borby s nimi v Rossii i stranax SNG (po materialam koordinatsionnyx ochetov). Epizootology, epidemiology and monitoring of parasitic diseases // Rossiyskiy parazitologicheskiy zurnal. - 2014. - No. 2. - S. 43-50.
19. Yarmukhamedova N. A. i dr. Clinical and epidemiological aspects of neurobrucellosis according to the information of Samarkand municipal infectious diseases hospital //Vestnik nauki i obrazovaniya. - 2020. - No. 14-2. - S. 61-66.