EKSTRANODAL SHIKASTLANISHLARI BO‘LGAN DIFFUZ YIRIK B-HUJAYRALI LIMFOMA BILAN OG‘RIGAN BEMORLARNING KLINIK KECHISHI VA DIAGNOSTIKASI XUSUSIYATLARI

Authors

  • Qobilov O.R Author
  • Niyozova Sh.X Author
  • Sobirjonov I.I Author

Keywords:

diffuz yirik B-hujayrali limfoma; ekstranodal shikastlanish; klinik kechish.

Abstract

Tadqiqotga 2015 yildan 2021 yilgacha tekshiruv va davolanishdan o‘tgan ekstranodal shikastlanishlari bo‘lgan diffuz yirik B-hujayrali limfoma bilan kasallangan 81 nafar bemor kiritilgan. Ushbu kasallik shakli bilan og‘rigan bemorlarni olti yillik kuzatuv davomida o‘rganish natijasida, bir xil davolash usullariga qaramay, besh yillik omon qolish darajasi 60,5% ni tashkil etdi. 32 (39,5%) bemorda esa davolash jarayonida patologik jarayonning progressiyasi tufayli o‘lim holatlari kuzatildi.

References

1. James O Armitage How I treat patients with diffuse large B-cell lymphoma. 2017 Jul 1;110(1):29-36.

2. Swerdlow S, Campo E, Harris N, et al. WHO Classification of tumours of haematopoietic and lymphoid tissues. Revised 4th edition ed. Lyon, France: IARC; 2017.

3. Cartwright R.A., McKinney P.A., O'Brien C. et al. // Non-Hodgkin's lymphoma: case control epidemiological study in Yorkshire // Leuk. Res.-2018.- Vol. 12 P.81-88;

4. Harris N.L., Jaffe E.S., Stein H. et al. // A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group // Blood 2014. Vol. 84. - P. 1361-1392;

5. Alaggio, R., Amador, C., Anagnostopoulos, I. et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia 36, 1720–1748 (2022).

6. Miller T.P.; Dahlberg S.; Cassady J.R. et al. Chemotherapy alone compared with chemotherapy plus radiotherapy for localized intermediate- and high-grade non-Hodgkin"s lymphoma. N Engl J Med. 2018;339(1):21-6.

7. Shenkier T.N.; Voss N.; Fairey R. et al. Brief chemotherapy and involved-region irradiation for limited-stage diffuse large-cell lymphoma: an 18-year experience from the British Columbia Cancer Agency. J Clin Oncol. 2022;20(1):197-204.

8. Horning S.J.; Weller E.; Kim K. et al. Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin"s lymphoma: Eastern Cooperative Oncology Group study 1484. J Clin Oncol. 2014;22(15):3032-8.

Published

2025-11-23

How to Cite

[1]
2025. EKSTRANODAL SHIKASTLANISHLARI BO‘LGAN DIFFUZ YIRIK B-HUJAYRALI LIMFOMA BILAN OG‘RIGAN BEMORLARNING KLINIK KECHISHI VA DIAGNOSTIKASI XUSUSIYATLARI. Ustozlar uchun. 84, 1 (Nov. 2025), 346–354.