INCIDENCE OF CHRONIC MYELOPROLIFERATIVE DISORDERS IN UZBEKISTAN
Keywords:
Keywords: chronic myeloproliferative disorders, chronic myeloid leukemia, epidemiology, incidence, Uzbekistan.Abstract
Abstract: Chronic myeloproliferative disorders (CMPDs) are a group of clonal hematopoietic stem cell diseases characterized by persistent proliferation of myeloid cell lineages in the bone marrow and peripheral blood. This group includes chronic myeloid leukemia, polycythemia vera, essential thrombocythemia, and primary myelofibrosis. The present study analyzes the incidence, epidemiological characteristics, and regional distribution of chronic myeloproliferative disorders in the Republic of Uzbekistan. The research is based on a retrospective analysis of available national publications and statistical reports. The results demonstrate that CMPDs are relatively rare in Uzbekistan; however, an increasing trend in detection has been observed in recent years, likely due to improvements in diagnostic methods and hematological services.
References
1. Tefferi A. Myeloproliferative Neoplasms. New England Journal of Medicine, 2020.
2. World Health Organization. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. WHO Press, 2016.
3. Goldman J.M., Melo J.V. Chronic Myeloid Leukemia. Hematology, 2018.
4. Salomova Y.N. Epidemiology of chronic myeloid leukemia in Uzbekistan. Tashkent Medical Academy, 2021.
5. Ministry of Health of the Republic of Uzbekistan. National hematology statistical reports.
