IMPACT OF ARTERIAL HYPERTENSION AND ENVIRONMENTAL FACTORS ON THE COURSE OF SYSTEMIC LUPUS ERYTHEMATOSUS IN CENTRAL ASIA
Keywords:
Keywords: systemic lupus erythematosus, arterial hypertension, Central Asia, environmental factors, viral infections, psychosocial stress, nephritis.Abstract
Abstract. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by multisystem involvement and occurs predominantly in women of
reproductive age. In Central Asian countries, a high prevalence of arterial hypertension,
intense solar radiation, environmental factors, and psychosocial stress may contribute
to a more severe course of SLE. The aim of this study was to evaluate the impact of
arterial hypertension and other environmental and psychosocial factors on the course
of SLE among the population of Central Asia. The study included 120 patients with
SLE (110 women and 10 men) aged 18–50 years. The following parameters were
assessed: arterial blood pressure, exposure to sunlight, environmental conditions,
history of viral infections, and psychosocial stress. The results showed that arterial
hypertension, excessive solar radiation, environmental factors, and psychosocial stress
exacerbate the course of SLE. Control of these factors may improve disease outcomes.
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