PREVALENCE OF OROFACIAL PAIN: CONSISTENT GENDER PREDOMINANCE AND AGE-RELATED VARIATIONS ACROSS STUDIES

Authors

  • Kalanov A.B. Author
  • Abdukadirov E.I. Author
  • Inoyatova S.O. Author
  • Abdullayeva M.B. Author
  • Tairova D.Z. Author

Keywords:

Keywords: Orofacial pain, Temporomandibular disorders, Prevalence, Gender differences, Age variations, Epidemiology

Abstract

Abstract. Background: Orofacial pain, including temporomandibular disorders (TMD), represents a major chronic pain condition with significant impacts on quality of life. This narrative synthesis reviews contemporary epidemiological evidence on the prevalence of orofacial pain and TMD, focusing on gender and age variations.

References

1. Ananthan S, Benoliel R. Chronic orofacial pain. J Neural Transm (Vienna). 2020;127(4):575-588.

2. Alqutaibi AY, Alhammadi MS, Hamadallah HH, et al. Global prevalence of temporomandibular disorders: a systematic review and meta-analysis. J Oral Facial Pain Headache. 2025;39(2):48-65.

3. Valesan LF, Da-Cas CD, Réus JC, et al. Prevalence of temporomandibular joint disorders: a systematic review and meta-analysis. Clin Oral Investig. 2021;25(2):441-453.

4. Wu S, Zhang W, Yan J, Noma N, Young A, Yan Z. Worldwide prevalence estimates of burning mouth syndrome: a systematic review and meta-analysis. Oral Dis. 2022;28(6):1431-1440.

5. Bäck K, Hakeberg M, Wide U, Hange D, Dahlström L. Orofacial pain and its relationship with oral health-related quality of life and psychological distress in middle-aged women. Acta Odontol Scand. 2020;78(1):74-80.

6. Häggman-Henrikson B, Liv P, Ilgunas A, et al. Increasing gender differences in the prevalence and chronification of orofacial pain in the population. Pain. 2020;161(8):1768-1775.

7. Del Rossi A, Di Spirito F, Cannavale R, et al. Prevalence of orofacial and head pain: an umbrella review of systematic reviews. J Oral Facial Pain Headache. 2024;38(3):213-228.

8. Musella G, Canfora F, Caponio VCA, et al. Oral dysaesthetic and perceptual disorder, a distinct subset of chronic orofacial pain without burning symptoms: a case-control study. J Oral Rehabil. 2025;52(4):567-578.

9. Lövgren A, Vallin S, Häggman-Henrikson B, et al. Women are worse off in developing and recovering from temporomandibular disorder symptoms. Sci Rep. 2025;15(1):4732.

10. Song QX, Zhang YY, Li YL, et al. The crucial role of NR2A mediating the activation of satellite glial cells in the trigeminal ganglion contributes to orofacial inflammatory pain during TMJ inflammation. Mol Neurobiol. 2025;62(3):1247-1265.

11. Cebola PMT, Lourenço AS, Hoppe AM, et al. Prevalence and interplay of hypervigilance and kinesiophobia in TMD patients: implications in clinical outcomes. J Oral Rehabil. 2025;52(10):1549-1558.

12. Zieliński G, Byś A, Baszczowski G, et al. Clinical profile in relation to age and gender of patients with temporomandibular disorders: a retrospective study. BMC Oral Health. 2024;24(1):947.

13. Qin S, Liu J, Fan JX, Qin Z, Jia J. Advances in orofacial pain research: a bibliometric analysis. Front Neurol. 2025;16:1609437.

14. Feng Y, Yang YF, Feng YZ, Guo Y. Measurement invariance of the Manchester Orofacial Pain Disability Scale (MOPDS) for biopsychosocial factor among orofacial patients and nonclinical populations: an evidence for clinical investigations. J Oral Rehabil. 2025;52(11):2074-2083.

15. Alqutaibi AY, Alhammadi MS, Hamadallah HH, et al. Global prevalence of temporomandibular disorders: a systematic review and meta-analysis. J Oral Facial Pain Headache. 2025;39(2):48-65.

16. Lövgren A, Vallin S, Häggman-Henrikson B, et al. Women are worse off in developing and recovering from temporomandibular disorder symptoms. Sci Rep. 2025;15(1):4732.

17. Exposto FG, Castrillon EE, Exposto CR, et al. Prevalence of painful temporomandibular disorders and overlapping primary headaches among young adults. Eur J Pain. 2025;29(5):e70013.

18. Zieliński G, Byś A, Baszczowski G, et al. Clinical profile in relation to age and gender of patients with temporomandibular disorders: a retrospective study. BMC Oral Health. 2024;24(1):947.

19. Del Rossi A, Di Spirito F, Cannavale R, et al. Prevalence of orofacial and head pain: an umbrella review of systematic reviews. J Oral Facial Pain Headache. 2024;38(3):213-228.

20. de Souza, A. L., & Fonseca, R. B. (2023). Pharmacological therapy in the management of temporomandibular disorders and orofacial pain: A systematic review and meta-analysis. BMC Oral Health, 23(1), 1–13. https://doi.org/10.1186/s12903-023-03524-8

Published

2026-01-12

How to Cite

Kalanov A.B., Abdukadirov E.I., Inoyatova S.O., Abdullayeva M.B., & Tairova D.Z. (2026). PREVALENCE OF OROFACIAL PAIN: CONSISTENT GENDER PREDOMINANCE AND AGE-RELATED VARIATIONS ACROSS STUDIES. JOURNAL OF NEW CENTURY INNOVATIONS, 92(1), 450-457. https://journalss.org/index.php/new/article/view/14714