ENDOPHYTIC MICROORGANISMS AND THEIR BIOLOGICALLY ACTIVE METABOLITES

Authors

  • Vakhobova Durdona Sherali qizi Author
  • U.K.Yusupov Author

Keywords:

Keywords: endophytic microorganisms, secondary metabolites, bioactive compounds, antimicrobial, anticancer, biocontrol, pharmaceutical biotechnology, plant growth promotion, genome mining.

Abstract

Abstract: Endophytic microorganisms are a diverse group of bacteria, fungi, actinomycetes, and even rare archaea that colonize healthy plant tissues without causing any immediate or overt disease symptoms. These microorganisms establish complex interactions with their host plants, and as a result of coevolution they produce a multitude of secondary metabolites with significant ecological, medical, and industrial importance. The study of endophytic microorganisms and their metabolites has significantly expanded in recent decades due to their enormous potential in pharmaceutical, agricultural, and environmental applications.

References

1. Arbeeny CM. Addressing the unmet medical need for safe and effective weight loss therapies. Obes Res 2004;12:1191–1196.

2. Khaodhiar L, McCowen KC, Blackburn GL. Obesity and its comorbid conditions. Clin Cornerstone. 1999;2:17–31.

3. Heck AM, Yanovski JA, Calis KA. Orlistat, a new lipase inhibitor for the management of obesity. Pharmacotherapy. 2000 Mar;20(3):270–279.

4. Gupta M, Saxena S, Goyal D. Potential pancreatic lipase inhibitory activity of an endophytic Penicillium species. J Enzyme Inhib Med Chem. 2015;30:15–21.

5. Hazalin N.A., Ramasamy K., Lim S.M., Wahab I.A., Cole A.L.J., Majeed A.A. Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia. BMC Complementary and Alternative Medicine. 2009;9:46.

6. Singh R., Gupta N., Goswami V.K., Gupta R. A simple staining protocol for lipases and esterases. Applied Microbiology and Biotechnology. 2006;70:679–682.

Published

2026-03-27

How to Cite

Vakhobova Durdona Sherali qizi, & U.K.Yusupov. (2026). ENDOPHYTIC MICROORGANISMS AND THEIR BIOLOGICALLY ACTIVE METABOLITES. JOURNAL OF NEW CENTURY INNOVATIONS, 97(1), 285-288. https://journalss.org/index.php/new/article/view/22784