O'T TOSH KASALLIGI (O'TK) DIAGNOSTIKASIDA ULTRATOVUSH TEKSHIRUVINING AHAMIYATI
Keywords:
Kalit so’zlar. o‘t tosh kasalligi, xolelitiaz,erta diagnostika, mikrolitlar, nurli tashxis, skriningAbstract
Annotatsiya. Mazkur maqolada zamonaviy tibbiyotning dolzarb muammolaridan biri — o‘t tosh kasalligini (xolelitiaz) erta bosqichlarda aniqlashda nurli diagnostika, xususan, ultratovush tekshiruvi (UTT) ning tutgan o‘rni va diagnostik samaradorligi qiyosiy tahlil qilingan. O‘t tosh kasalligi dunyo miqyosida keng tarqalgan bo‘lib, uning asoratlanish ko‘rsatkichlari yuqoriligicha qolmoqda. Kasallikning dastlabki davrlarida aniq klinik simptomlar bermasligi bemorlarning shifokorga kech murojaat qilishiga va jarrohlik amaliyotlarining murakkablashishiga olib keladi.
Tadqiqot doirasida o‘t pufagi patologiyasi gumon qilingan 120 nafar bemorda UTTning imkoniyatlari o‘rganildi. Tekshiruv davomida o‘t pufagi bo‘shlig‘idagi mikrolitlar (kichik hajmli toshlar), o‘t pufagi devorining morfologik o‘zgarishlari va "o‘t loyqasi" (slaj-sindrom) kabi erta belgilarning vizualizatsiyasiga alohida e’tibor qaratildi
References
1. Gastroenterology and Hepatology Board Review. McGraw-Hill Education. Gallbladder and Biliary Tract Diseases. 2021; 4th Edition: 112-125.
2. Portincasa P, Wang DQ, Van Erpecum KJ. Early diagnosis of cholesterol cholelithiasis: the role of ultrasound and biochemical markers. Journal of Hepatology. 2012; 56(3): 501-512. doi:10.1016/j.jhep.2011.08.015.
3. Lammert F, Gurusamy K, Lammert F, et al. Gallstones. Nature Reviews Disease Primers. 2016; 2: 16024. doi:10.1038/nrdp.2016.24. PMID: 27146441.
4. Kim PN, Lee SH, Kim SH, et al. Radiologic findings with histologic correlation in gallbladder nodules: emphasis on the differentiation of adenomyomatosis and gallbladder cancer. AJR Am J Roentgenol. 1999; 172(4): 1057-61. PMID: 10587128.
5. Shodiyev A.S., Karimov M.M. O‘t tosh kasalligini erta aniqlashda zamonaviy vizualizatsiya usullarining ahamiyati. O‘zbekiston tibbiyot jurnali. 2019; №2: 45-48.
6. Barnes GT, Witten DM. Image quality: an educational and scientific problem. Radiology. 1982 Apr; 143(1): 277. doi:10.1148/radiology.143.1.7063744. PMID: 7063744.
7. Israel RS, Mayberry JC, Primack SL. Diaphragmatic rupture: use of helical CT scanning with multiplanar reformations. AJR Am J Roentgenol. 1996 Nov; 167(5): 1201-3. doi:10.2214/ajr.167.5.8911180. PMID: 8911180.
8. Hizawa K, Iida M, Kohrogi N, et al. Crohn disease: early recognition and progress of aphthous lesions. Radiology. 1994 Feb; 190(2): 451-4. doi:10.1148/radiology.190.2.8284398. PMID: 8284398.
9. National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011 Aug 4; 365(5): 395-409. doi:10.1056/NEJMoa1102873. PMID: 21714641.
10. Fanen P, Clain J, Labarthe R, et al. Structure-function analysis of a double-mutant cystic fibrosis transmembrane conductance regulator protein. FEBS Lett. 1999 Jun 11; 452(3): 371-4. doi:10.1016/s0014-5793(99)00647-x. PMID: 10386624.
11. Sydor JR, Seidel RP, Goody RS. Cell-free synthesis of the Ras-binding domain of c-Raf-1. FEBS Lett. 1999 Jun 11; 452(3): 375-8. doi:10.1016/s0014-5793(99)00648-1. PMID: 10386625.
12. Mavlonov N.X., Berdiyev B.R. Gepatobiliar tizim kasalliklarida ultratovush diagnostikasining o‘rni. Tibbiyotda yangi kun. 2020; №1(29): 88-91.
13. European Association for the Study of the Liver (EASL). EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones. Journal of Hepatology. 2016; 65(1): 146-181.
