EPIDEMIOLOGY OF BONE TUMORS
Keywords:
bone tumors, epidemiology, classification, pathologyAbstract
Primary bone tumors are uncommon and this has certainly contributed to the
scarcity of data about their relative frequency, and to the limited understanding of the
risk factors. Overall, bone sarcomas account for 0.2% of all malignancies, and the
adjusted incidence rate for all bone and joint malignancies is 0.9 per 100,000 persons
per year, while the 5-year overall survival rate is 67.9%. The age specific incidence
rates of bone sarcomas show a bimodal distribution, with a first peak occurring in the
second decade, and a second peak occurring in patients older than sixty, in relation
with the age distribution of the main histological subtypes.
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