EARLY DIAGNOSIS AND PROGNOSIS OF HEMORRHAGIC VASCULITIS USING MODERN LABORATORY BIOMARKERS
Keywords:
hemorrhagic vasculitis, laboratory biomarkers, endothelial dysfunction, inflammation.Abstract
Hemorrhagic vasculitis (Henoch–Schönlein purpura, IgA
vasculitis) is a common immune-inflammatory disease in children, affecting the skin,
joints, gastrointestinal tract, and kidneys. The clinical heterogeneity and severity of the
disease determine the prognosis and treatment strategy. Traditional laboratory tests-
urinalysis, C-reactive protein, ESR assist in assessing disease activity, but their ability
to detect severe forms early is limited. Modern laboratory biomarkers play a key role
in early diagnosis, identification of severe forms, and prediction of renal complications.
A comprehensive clinical and laboratory approach enables timely diagnosis of
hemorrhagic vasculitis in children, prevents the progression of severe forms, and
reduces the risk of long-term complications.
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