UZBEKISTAN ITENKO-CUSHING
Keywords:
pituitary adenoma, adrenocorticotropic hormone, corticotrophinolysis hormone, ACTH hypersecretion, Cushing's disease.Abstract
Cushing's disease is considered a rare disease characterized by
hypersecretion of adrenocorticotropic hormone (ACTH) due to pituitary adenoma,
which ultimately leads to endogenous hypercorticism by stimulating the adrenal
glands. Clinical signs indicating Cushing's disease, such as obesity, moon face,
hirsutism and an abundance of faces, are already present in the presentation.
Endogenous hypercorticism is associated with cardiovascular and metabolic
manifestations, as well as with an increased risk of respiratory diseases, mental
complications, osteoporosis and infections, which leads to high levels of morbidity and
mortality. It is very important to diagnose Cushing's disease as early as possible and
implement a treatment plan that can lead to a successful prognosis and a small number
of complications.
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