DIAGNOSTIC POTENTIAL OF ENZYME-LINKED IMMUNOSORBENT ASSAY IN CLINICAL PRACTICE
Keywords:
enzyme-linked immunosorbent assay, ELISA, laboratory diagnostics, antigen- antibody reaction, clinical practice.Abstract
Enzyme-linked immunosorbent assay (ELISA) is one of the most widely
used immunological methods in modern laboratory diagnostics. This method is
characterized by high sensitivity and specificity and plays an important role in the
diagnosis of various infectious, autoimmune, endocrine, and oncological diseases. The
present review article analyzes the theoretical basis of ELISA, its diagnostic potential
in clinical practice, major advantages, and existing limitations based on contemporary
scientific literature. The comprehensive application of ELISA in clinical laboratory
practice enables early disease detection, effective monitoring, and evaluation of
therapeutic efficacy.
References
1. Иммуноферментный анализ: Пер. с англ. / Под ред. Т. Нго, Г. Ленхоффа. – М.: Мир, 1988. – 446 с.
2. Теория и практика иммуноферментного анализа / А.М. Егоров [и др.]. –
М.:
Высш. школа, 1991. – 288 с.
3. Ярилин, А.А. Иммунология / А.А. Ярилин. – М.: ГЭОТАР-Медиа, 2010. –
752 c.
4. Ройт, А. Иммунология. Пер. с англ./ А.Ройт, Дж. Бростофф. Д.Мейл. – М.:
Мир, 2000. – 592 с.