SPECIFICITY OF MICROFLORA IN PATIENTS WITH DIFFERENT TYPES AND MATERIALS OF DENTAL PROSTHESES
Keywords:
dental prostheses, oral microflora, surface roughness, zirconia, titanium, Candida albicans, Streptococcus mutans, peri-implantitis, biofilm diversity, prosthetic materials.Abstract
This study investigates the relationship between dental prosthesis
materials and the composition of oral microflora among 80 adult patients using
different prosthesis types: removable acrylic, fixed metal-ceramic, zirconia-based, and
titanium implant-supported restorations. Standardized clinical examinations,
microbiological cultures, and quantitative PCR analyses were performed to assess
microbial diversity, load, and surface characteristics. The results showed that acrylic
resin dentures harbored the highest microbial load (45.6×10^5 CFU/mL) dominated by
Candida albicans and Streptococcus mutans, while zirconia and titanium prostheses
exhibited reduced biofilm formation and higher microbial diversity (Shannon index
2.10). Surface roughness strongly correlated with total microbial load (r=0.89). These
findings underscore that smoother materials such as zirconia and titanium minimize
microbial accumulation, reducing the risk of denture stomatitis, secondary caries, and
peri-implant inflammation. Clinically, the study highlights the importance of material
selection, finishing protocols, and individualized hygiene programs to enhance
prosthesis longevity and oral health outcomes.
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