MODERN APPROACHES TO THE CLINICAL MANAGEMENT AND TREATMENT OF CRIMEAN-CONGO HEMORRHAGIC FEVER

Abstract

 This article provides a comprehensive literature review on the 
clinical description and treatment approaches for Crimean-Congo hemorrhagic fever 
(CCHF). The paper summarizes epidemiological data, clinical features, and therapeutic 
interventions described in contemporary research. It highlights that CCHF remains a 
serious zoonotic infection with a high fatality rate, predominantly affecting regions of 
Asia, Africa, and Eastern Europe. The analysis of recent studies reveals that early 
administration of ribavirin and intensive supportive therapy can reduce mortality, 
although their efficacy varies. Current investigations focus on the development of new 
antiviral agents and immunotherapeutic options. The review emphasizes the need for 
early diagnosis, adequate supportive management, and strict infection control to 
improve clinical outcomes and prevent nosocomial transmission.