THE IMPACT OF INFECTIOUS DISEASES ON EXACERBATIONS OF BRONCHIAL ASTHMA
Keywords:
bronchial asthma; infectious diseases; exacerbation; respiratory viruses; inflammation; asthma controlAbstract
Bronchial asthma (BA) remains one of the most prevalent chronic
respiratory diseases worldwide, affecting approximately 300 million people. Despite
advances in pharmacological treatment and patient education, acute exacerbations
remain a significant clinical and socioeconomic problem. One of the most frequent
triggers of asthma exacerbations is infection of the upper or lower respiratory tract,
both viral and bacterial. Viral infections - especially those caused by rhinoviruses,
influenza, and respiratory syncytial virus - are known to enhance airway inflammation
and hyperresponsiveness, resulting in worsening of asthma control.
The present study aimed to evaluate the impact of acute infectious diseases on the
frequency and severity of asthma exacerbations among adult patients, and to analyze
the relationship between specific pathogens and the clinical course of bronchial asthma.
References
Further studies involving larger populations and molecular analysis of pathogen
host interactions are necessary to develop targeted preventive and therapeutic
interventions aimed at minimizing infection-related asthma morbidity.
