THE PROGNOSTIC ROLE OF EGFR AND VEGF IN COLORECTAL CANCER RECURRENCE
Keywords:
Significant differences in receptor expression were observed between patients with and without recurrence. EGFR positivity was present in 74.5% of relapsed patients versus 52.1% in non-relapsed cases (p=0.018). VEGF positivity was found in 80% of relapsed patients versus 50% of controls (p=0.001). Negative receptor status was associated with a markedly lower risk of recurrence, with odds ratios of 2.694 for EGFR and 4.000 for VEGF.Abstract
To evaluate whether the expression levels of epidermal growth factor receptor
(EGFR) and vascular endothelial growth factor (VEGF) can predict recurrence in
colorectal cancer patients, thereby aiding personalized treatment strategies.
References
EGFR and VEGF overexpression are strongly associated with higher risk of
colorectal cancer recurrence. These markers could serve as valuable prognostic
indicators and therapeutic targets, supporting the development of personalized
treatment approaches to improve patient outcomes. Further studies are warranted to
validate these findings and optimize clinical application.
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Published
2025-11-01
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How to Cite
THE PROGNOSTIC ROLE OF EGFR AND VEGF IN COLORECTAL CANCER RECURRENCE. (2025). ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 80(3), 93-94. https://journalss.org/index.php/obr/article/view/4176
