METABOLIK SINDROMNING FENOTIPLARI
Keywords:
Metabolik sindrom, fenotiplar, ko‘p tomirli koronar arteriya kasalligi (KAK), tomir qattiqligi, puls to‘lqini tezligi (PWV)Abstract
Metabolik sindrom (MS) — yurak-qon tomir kasalliklari
rivojlanishida muhim risk faktor bo‘lib, u turli fenotiplarga ega. Har bir fenotip yurak
qon tomir tizimiga turlicha ta’sir ko‘rsatadi va ko‘p tomirli koronar arteriya
shikastlanishi hamda tomir qattiqligi parametrlariga sezilarli farq olib keladi. Ushbu
maqolada metabolik sindromning asosiy fenotiplari — obesitet asosidagi,
insulinrezistent va diabetik fenotiplar — solishtirilib, ularning koronar arteriya
shikastlanishi darajasi va arterial stiffness ko‘rsatkichlariga ta’siri o‘rganildi. Natijalar
fenotiplarga qarab farqlilik mavjudligini ko‘rsatadi, bu esa MS bilan og‘rigan
bemorlarni risk jihatdan aniqlash va individual yondashuvni ishlab chiqishda
muhimdir.
References
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2.
Kammerlander A,
Mayrhofer T,
Ferencik M,
Pagidipati N J,
Karady J,
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2021 Apr;44(4):1038-1045.
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2024;22:434.
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