STRESS, APPETITE, AND WEIGHT GAIN: NEUROENDOCRINE MECHANISMS LINKING CORTISOL AND EATING BEHAVIOR.

Authors

  • Botirova Nigina Akram qizi Author

Keywords:

chronic stress, cortisol, hypothalamic–pituitary–adrenal axis, neuroendocrine regulation, appetite control, emotional eating, hedonic eating, reward pathways

Abstract

Chronic psychological stress is a key driver of dysregulated eating behaviors and 
weight gain. Central to this relationship is cortisol, a glucocorticoid hormone produced 
by the adrenal cortex in response to activation of the hypothalamic–pituitary–adrenal 
(HPA) axis. While acute stress tends to suppress appetite, chronic stress leads to 
sustained cortisol secretion, which alters energy balance, promotes hedonic eating, and 
increases visceral adiposity. This review explores the neuroendocrine and behavioral 
mechanisms through which cortisol influences appetite regulation, macronutrient 
preference, and body fat distribution, emphasizing the interplay

References

1.

Adam, T. C., & Epel, E. S. (2007). Stress, eating, and the

reward system. Physiology & Behavior, 91(4), 449–458.

2.

Björntorp, P. (2001). Do stress reactions cause abdominal

obesity and comorbidities? Obesity Reviews, 2(2), 73–86.

3.

Dallman, M. F., et al. (2003). Chronic stress and comfort

foods: Self-medication and abdominal obesity. Brain, Behavior, and Immunity, 17(4),

223–233.

4.

Epel, E. S., et al. (2000). Stress may add bite to appetite

in women: A laboratory study of stress-induced cortisol and eating behavior.

Psychoneuroendocrinology, 26(1), 37–49.

5.

McEwen, B. S. (2007). Physiology and neurobiology of

stress and adaptation: Central role of the brain. Physiological Reviews, 87(3), 873–904.

6.

Rouach, V., et al. (2007). The acute ghrelin response to

psychosocial

stress

is

related

to

Psychoneuroendocrinology, 32(7), 703–708.

7.

cortisol

and

perceived

stress.

АТЕРОКАЛЬЦИНОЗ РИВОЖЛАНИШИДА ЭНДОКРИН ТИЗИМ

БУЗИЛИШЛАРИНИНГ РОЛИ

ММ Асадуллаев, ХТ Мирахмедова, НА Ботирова – 2024

8.

ЭНДОКРИННАЯ СИСТЕМА И АТЕРОМАТОЗНЫЕ СТАДИИ

АТЕРОСКЛЕРОЗА

НА Ботирова, НМ Вахабова, ХТ Мирахмедова… - 2024

Published

2025-11-30

How to Cite

STRESS, APPETITE, AND WEIGHT GAIN: NEUROENDOCRINE MECHANISMS LINKING CORTISOL AND EATING BEHAVIOR. (2025). ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 82(2), 301-305. https://journalss.org/index.php/obr/article/view/7150