STUDY OF CLINICAL, LABORATORY, AND IMMUNOLOGICAL FEATURES IN PATIENTS WITH BRONCHOPULMONARY DISEASES
Abstract
Abstract. Bronchopulmonary diseases remain a significant medical problem due
to their chronic course and frequent complications. This study evaluates clinical
manifestations, laboratory findings, and immunological parameters in patients with
bronchopulmonary pathology. The analysis focused on inflammatory activity,
hematological changes, and immune system responsiveness. The findings demonstrate
that early inflammatory responses and immune imbalance are common even in the
initial stages of the disease, highlighting the importance of timely diagnosis and
individualized treatment strategies.
Diseases of the bronchopulmonary system, such as chronic bronchitis,
pneumonia, and bronchial asthma, are widely prevalent and often associated with
immune dysfunction and recurrent infections. The chronic nature of these conditions
contributes to persistent inflammatory processes and alterations in the body’s defense
mechanisms. Recent studies suggest that immunological disturbances play a key role
in disease progression. Therefore, a comprehensive evaluation of clinical, laboratory,
and immune parameters is essential for improving diagnostic accuracy and therapeutic
outcomes.
The aim of this study was to assess clinical, laboratory, and immunological
changes in patients with bronchopulmonary diseases and to formulate evidence-based
recommendations for optimizing diagnostic and treatment approaches.
The study involved 120 patients diagnosed with bronchopulmonary pathology
who received inpatient treatment between 2022 and 2024. The control group included
30 apparently healthy individuals. Clinical assessment was combined with laboratory
investigations, including complete blood count and biochemical analysis, as well as
immunological evaluation of CD4+, CD8+, IgA, IgM, and IgG levels. Statistical
processing was carried out using SPSS software, applying Student’s t-test, χ² test, and
correlation analysis.
