CLINICAL AND LABORATORY FEATURES OF ACUTE VIRAL HEPATITIS IN THE REPUBLIC OF KARAKALPAKSTAN
Keywords:
Keywords: Acute viral hepatitis, HAV, HBV, HEV, clinical features, laboratory findings, KarakalpakstanAbstract
Acute viral hepatitis (AVH) remains a significant public health concern in the
Republic of Karakalpakstan, contributing to high morbidity among adults and children.
This study aimed to evaluate the clinical presentations and laboratory findings of
patients with AVH in the region. A total of 125 patients with confirmed AVH were
included. Clinical symptoms, biochemical parameters, and serological markers were
analyzed. Fever, jaundice, and hepatomegaly were the most common clinical
manifestations. Elevated levels of alanine aminotransferase (ALT) and aspartate
aminotransferase (AST) were observed in 88% and 85% of patients, respectively.
Serological tests revealed hepatitis A virus (HAV) in 42%, hepatitis B virus (HBV) in
35%, and hepatitis E virus (HEV) in 18% of cases. These findings provide important
insights into the epidemiology and laboratory characteristics of AVH in
Karakalpakstan, which may guide early diagnosis, management, and prevention
strategies.
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