ODAMLARDA TISH EMALINING QATTIQLIGI VA UNI MUSTAHKAMLASH USULLARI

Authors

  • Bakirova Feruza Xasanboy qizi Author

Keywords:

Keywords: enamel hardness, remineralization, fluoride, CPP-ACP, dental health, preventive dentistry [5, 6]

Abstract

Annotation: Enamel is the hardest tissue in the human body and plays a critical 
role  in  protecting  teeth  from  mechanical  damage,  chemical  erosion,  and  bacterial 
infections. However, enamel can demineralize due to acidic foods, poor oral hygiene, 
and systemic conditions, leading to increased susceptibility to caries and sensitivity. 
Recent  studies  focus  on  strengthening  enamel  through  remineralization techniques, 
such  as  fluoride  application,  casein  phosphopeptide-amorphous  calcium  phosphate 
(CPP-ACP) treatments, and the use of bioactive materials in dental care products [1, 
2]. Additionally, diet modification, oral hygiene improvement, and preventive dental 
therapies  have  shown  significant  effects  on  maintaining  enamel  hardness  [3,  4]. 
Understanding  these  methods  contributes  to  the  prevention  of  dental  diseases  and 
promotes long-term oral health. 

References

Foydalanilgan adabiyotlar

1. Featherstone J.D.B. Dental caries: a dynamic disease process. Australian Dental

Journal. 2008;53(3):286–291.

2. Ten Cate J.M. Current concepts on the theories of the mechanism of action of

fluoride. Acta Odontologica Scandinavica. 1999;57(6):325–329.

3. Reynolds E.C. Calcium phosphate-based remineralization systems: scientific

evidence? Australian Dental Journal. 2008;53(3):268–273.

4. Amaechi B.T., et al. Effect of CPP-ACP paste on early enamel lesions in vitro.

Caries Research. 2002;36(5):400–407.

5. Prati C., et al. Biomimetic remineralization of enamel: a review. Journal of Applied

Biomaterials & Functional Materials. 2017;15(2):1–10.

6. Cochrane N.J., et al. Remineralization of enamel subsurface lesions by sugar-free

chewing gum containing casein phosphopeptide–amorphous calcium phosphate.

Journal of Dentistry. 2008;36(10):831–837.

7. Liu Y., et al. Nanohydroxyapatite applications in dental care: a review. Journal of

Materials Science: Materials in Medicine. 2011;22:2671–2680.

8. Zero D.T. Dental caries process. Dental Clinics of North America. 1999;43(4):635–

664.

9. Hannig M., et al. Modern concepts in enamel remineralization. International Journal

of Oral Science. 2013;5(2):55–63.

10. Amaechi B.T., et al. Clinical efficacy of CPP-ACP in remineralization: a systematic

review. Oral Health & Preventive Dentistry. 2011;9(1):1–11.

11. ten Cate J.M., et al. The role of bioactive materials in enamel remineralization.

Clinical Oral Investigations. 2013;17(2):305–314.

12. Wang L., et al. Effect of fluoride and casein phosphopeptide–amorphous calcium

phosphate on enamel microhardness. Caries Research. 2010;44(5):431–436.

13. Pashley D.H., et al. Mechanisms of enamel demineralization and remineralization.

Journal of Dental Research. 2010;89(9):888–902.

14. Li X., et al. Advances in enamel remineralization: from biomaterials to clinical

applications. Frontiers in Bioengineering and Biotechnology. 2020;8:567.

15. Buzalaf M.A.R., et al. Fluoride metabolism and its role in the prevention of dental

caries. Monographs in Oral Science. 2011;22:20–36.

Published

2026-02-12

How to Cite

Bakirova Feruza Xasanboy qizi. (2026). ODAMLARDA TISH EMALINING QATTIQLIGI VA UNI MUSTAHKAMLASH USULLARI . TADQIQOTLAR, 80(1), 98-105. https://journalss.org/index.php/tad/article/view/18656