OIV VA CD4 HUJAYRALARI O‘RTASIDAGI PATOFIZIOLOGIK ALOQALAR HAMDA TERAPEVTIK TIKLANISH MEXANIZMLARI
Keywords:
Kalit so‘zlar: OIV, CD4 hujayralari, T-helperlar, retrovirus, replikatsiya, opportunistik infeksiyalar, antiretrovirus terapiya (ART), OITS.Abstract
Annotatsiya: Ushbu maqolada Odam immun tanqisligi virusining (OIV) inson
immun tizimining asosiy bo‘g‘ini bo‘lmish CD4 hujayralari bilan o‘zaro ta’siri
o‘rganiladi. Virusning hujayra ichiga kirishi, replikatsiyasi va immun tizimini falaj
qilish bosqichlari tahlil qilingan. Shuningdek, antiretrovirus terapiyasining (ART)
virus yukini kamaytirish va CD4 hujayralari populyatsiyasini qayta tiklashdagi o‘rni
yoritilgan.
References
Foydalanilgan adabiyotlar
1. UNAIDS. Global HIV & AIDS statistics — 2024 fact sheet.
2. Pauza, C. D., et al. (2022). CD4 T-Cell Recovery in HIV-1 Infection. Journal of
Immunology Research.
3. WHO. (2025). Consolidated guidelines on HIV prevention and treatment.
4. Alimova, N. X. (2023). OIV infeksiyasida immunologik ko‘rsatkichlar va ARV-terapiya
samaradorligi.
5. Finzi, D., et al. (2019). Latent reservoir of HIV-1 in T cells. Nature Medicine.
6. Gulick, R. M. (2021). Antiretroviral Therapy for HIV Infection. New England Journal of
Medicine.
