YOSH QIZLARDA TUXUMDON ENDOMETRIOZI RIVOJLANISHINING GISTOKIMYOVIY MARKERLARI VA TO‘QIMA DARAJASIDAGI METABOLIK-FAOL O‘ZGARISHLARNING PATOGENETIK AHAMIYATI
Keywords:
Kalit so‘zlar: tuxumdon endometriozi, gistokimyoviy markerlar, oksidlovchi stress, Ki-67, VEGF, TNF-α, metabolik o‘zgarishlar.Abstract
Annotatsiya. Ushbu tadqiqotda yosh qizlarda tuxumdon endometriozi
rivojlanishining gistokimyoviy markerlari va to‘qima darajasidagi metabolik-faol
o‘zgarishlarning patogenetik ahamiyati o‘rganildi. 20 nafar bemorda endometrioid
to‘qima biopsiyasi asosida oksidlovchi stress, proliferativ faollik va yallig‘lanish
mediatorlari darajasi baholandi. Olingan natijalar kasallik patogenezida hujayraviy
metabolizm buzilishlari va immun yallig‘lanish jarayonlarining yetakchi rolini
ko‘rsatdi.
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