INCREASED DENTAL IMPLANT OSTEOINTEGRATION IN MENOPAUSAL OSTEOPOROSIS IN WOMEN

Authors

  • Achilova Nodira Ganievna Author

Abstract

 
Introduction 
Osteoporosis is a systemic skeletal disease that is accompanied by a decrease in 
bone density and changes in bone microarchitecture, leading to increased fragility and 
a  high  risk  of  fractures[1][2].  According  to  WHO  data,  approximately  every  third 
woman and every fifth man over 50 suffers from osteoporosis[1][3]. In Russia, the 
prevalence  of  osteoporosis  among  women  after  50  years  is  ~33.8%,  among  men  - 
~26.9%[1]; the number of diagnosed patients is close to 14 million people[4][3]. In 
postmenopause  in  women,  calcium  leaching  from  bones  accelerates,  which  is 
especially relevant for dental implantation: insufficient bone volume of the alveolar 
ridge  can  limit  the  possibility  of  full-fledged  osteointegrative  implantation.  On  the 
other hand, dental implants are successfully implanted in patients with osteoporosis. 
Recent publications indicate high survival rates of implants (>90-95%) even in women 
with  osteoporosis[6][7].  Due  to  the  increasing  number  of  elderly  patients  and  the 
prevalence  of  osteoporosis,  the  task  of  ensuring  reliable  osseointegration  during 
menopause in women is becoming increasingly important both in maxillofacial surgery 
and in dental practice. The purpose of this work is to summarize modern data on the 
impact  of  osteoporosis  (including  drug-induced  osteoporosis  when  taking 
bisphosphonates)  on  the  osteointegration  of  dental  implants  in  women  during  the 
climacteric  period  and  to  examine  modern  approaches  (PRGF,  osteoplasty,  3D-
planning) to treating such patients. 

References

List of Literature (Alphabetical, GOST) :

1. Cho J.M., Lee S.J. Clinical outcomes and bone marker changes in postmenopausal

women with dental implants: a one-year prospective study // Int. J. Implant Dent.

2025. Vol.11. Art.41.

2. Giro G., Chambrone L., Goldstein A., et al. Impact of osteoporosis in dental

implants: A systematic review // World J. Orthop. 2015. Vol.6, No2. P.311-315.

3. Holahan C.M., Koka S., Kennel K.A., et al. Effect of osteoporotic status on the

survival of titanium dental implants // Int. J. Oral Maxillofac. Implants. 2008.

Vol.23, No5. P.905-910.

4. Khesin R.A., Kozlova M.V., Malichenko S.B., Goncharov Y.I. The osteo-

remodeling process in the jaw bones of elderly patients // Russ. J. Stomatol. Vol.7,

No.4. P.47-51.

5. Lemos C.A.A., de Oliveira A.S., Faé D.S., et al. Do dental implants placed in

patients with osteoporosis have higher risks of failure and marginal bone loss

compared to healthy patients? A systematic review with meta-analysis // Clin. Oral

Investig. 2023. Vol.27, No6. P.2483-2493.

6. Madrid C., Sanz M. What effect do systematically administered bisphosphonates

have on oral implant therapy? A systematic review // Clin. Oral Implants Res. 2009.

Vol.20, Suppl.4. P.87-95.

7. Mozzati M., Arata V., Giacomello M., et al. Failure risk estimates after dental

implant placement associated with growth factor-rich plasma-Endoret in

osteoporotic women under bisphosphonate therapy // J. Craniofac. Surg. 2015.

Vol.26, No3. P.749-755.

8. Tarasenko S.V., Ershova A.M. Application of synthetic osteoplastic materials to

increase the parameters of the alveolar bone of the human body before dental

implantation // Stomatology (Moscow).. 2017. Vol.96, No2. P.70-74.

9. Temmerman A., Rasmusson L., Kübler A., et al. A prospective, controlled,

multicenter study to evaluate the clinical outcome of implant treatment in women

with osteoporosis/osteopenia: 5-year results // J. Dent. Res. 2019. Vol.98, No1.

P.84-90.

10. Tardivo D., Delgado-Ruiz R.A., Marchesan M., et al. Applications of Growth

Factors in Implant Dentistry // Curr. Issues Mol. Biol. 2025. Vol.47, No5. Art.317.

11. World Osteoporosis Day 20.10.2022 | GBUZ PCKB1GBUZ PCKB1

https://pkkb1.ru/vsemirnyj-den-borby-osteoporozom/The osteo-remodeling

process in the jaw bones of older patients

12. https://www.mediasphera.ru/issues/rossijskaya-stomatologiya/2014/4/292072-

64062015048

13. Clinical outcomes and bone marker changes in postmenopausal women with dental

implants: a one-year prospective study | International Journal of Implant Dentistry

| Full Text

14. https://journalimplantdent.springeropen.com/articles/10.1186/s40729-025-00628-

4 researchgate.net

15. https://www.researchgate.net/profile/STarasenko/publication/316258083_Syntheti

c_osteoplastic_materials_for_alveolar_bone_augmentation_before_dental_implan

tation/links/5df9523ca6fdcc283728dcbe/Synthetic-osteoplastic-materials-for-

alveolar-bone-augmentation-before-dental-implantation.pdf

16. Failure risk estimates after dental implant placement associated with growth factor-

rich plasma-Endoret in osteoporotic women under bisphosphonate therapy -

PubMed

17. https://pubmed.ncbi.nlm.nih.gov/25974785/Impact of osteoporosis in dental

implants: A systematic review

18. https://www.wjgnet.com/2218-5836/abstract/v6/i2/311.htm

19. (PDF) Do dental implants placed in patients with osteoporosis have higher risks of

failure and marginal bone loss compared to healthy patients? Systematic review

with meta-analysis

20. https://www.researchgate.net/publication/369974039_Do_dental_implants_placed

_in_patients_with_osteoporosis_have_higher_risks_of_failure_and_marginal_bon

e_loss_compared_to_those_in_healthy_patients_A_systematic_review_with_meta

-analysis

21. Effect of osteoporotic status on the survival of titanium dental implants – PubMed

22. https://pubmed.ncbi.nlm.nih.gov/19014161/Applications of Growth Factors in

Implant Dentistry

23. https://www.mdpi.com/1467-3045/47/5/317

24. A Prospective, Controlled, Multicenter Study to Evaluate the Clinical Outcome of

Implant Treatment in Women with Osteoporosis/Osteopenia: 5-Year Results –

PubMed https://pubmed.ncbi.nlm.nih.gov/30205020/

Published

2025-12-23

How to Cite

Achilova Nodira Ganievna. (2025). INCREASED DENTAL IMPLANT OSTEOINTEGRATION IN MENOPAUSAL OSTEOPOROSIS IN WOMEN . Ta’lim Innovatsiyasi Va Integratsiyasi, 59(4), 194-200. https://journalss.org/index.php/tal/article/view/12478