HORMONAL STATUS AS A DETERMINANT OF FILLER CHOICE IN FERTILE-AGE WOMEN OF THE CENTRAL ASIAN POPULATION: A COMPARATIVE ANALYSIS
Abstract
Abstract
Relevance: Aesthetic facial correction using dermal fillers requires
consideration of ethnic skin characteristics and the influence of the patient’s hormonal
background [1, 2]. The hormonal profile of women of fertile age directly affects the
structural and functional properties of the skin, which must be taken into account when
planning injection techniques [9, 10].
Objective: To develop an algorithm for selecting dermal fillers for women of
fertile age in the Central Asian population, taking into account hormonal characteristics
and skin structure specifics.
Materials and Methods: A systematic analysis of literature data was performed,
including studies on Asian skin characteristics, hormonal profiles, and comparative
effectiveness of fillers.
References
References
1. Corduff N. et al. Current Practices in Hyaluronic Acid Dermal Filler Treatment in
Asia Pacific and Practical Approaches to Achieving Safe and Natural-Looking
Results // Clin Cosmet Investig Dermatol. – 2022. – Vol. 15. – P. 1213-1223.
2. Li H. et al. Detection of skin thickness and density in healthy Chinese individuals
using high-frequency ultrasound // Skin Res Technol. – 2022. – Vol. 29(1). – P.
e13219.
3. Hong J.Y. et al. A Multi-center, randomized, double blinded, comparative study of
two hyaluronic acid fillers for temporary restoration of mid-face volume in Asians
// J Cosmet Dermatol. – 2020. – Vol. 19(7). – P. 1619-1626.
4. Azziz R. et al. Androgen Excess in Women: Experience with Over 1000
Consecutive Patients // J Clin Endocrinol Metab. – 2004. – Vol. 89(2). – P. 453-462.
5. Dumesic D.A. et al. Scientific Statement on the Diagnostic Criteria, Epidemiology,
Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome // Endocr
Rev. – 2015. – Vol. 36(5). – P. 487-525.
6. Sultanova F. et al. Prevalence of insulin resistance and hyperandrogenemia in
women of reproductive age in Uzbekistan // J Endocrinol Invest. – 2021. – Vol.
44(8). – P. 1653-1660.
7. Kim J.J. et al. Androgen receptor gene CAG repeat polymorphism in women with
polycystic ovary syndrome // Fertil Steril. – 2008. – Vol. 90(6). – P. 2318-2323.
8. Amirova A. et al. Hormonal profile and metabolic parameters in women of
Kazakhstan with polycystic ovary syndrome // Central Asian Journal of Global
Health. – 2019. – Vol. 8(1). – P. 45-52.
9. Thornton M.J. Estrogens and aging skin // Dermatoendocrinol. – 2013. – Vol. 5(2).
– P. 264-270.
10. Zouboulis C.C. et al. Sexual hormones in human skin // Horm Metab Res. – 2007.
– Vol. 39(2). – P. 85-95.
11. Goodman G.J., Callan P., Carruthers J., et al. Global aesthetics consensus:
hyaluronic acid fillers and complications. Plast Reconstr Surg. 2020;146(4):436e–
445e.
12. Micheels P., Sarazin D., Tran C., Salomon D. Effect of different crosslinking
technologies on hyaluronic acid filler rheology and clinical performance. Dermatol
Surg. 2019;45(1):S33–S40.
13. Sundaram H., Voigts B., Beer K., Meland M. Comparison of the rheological
properties of hyaluronic acid dermal fillers. Dermatol Surg. 2010;36(Suppl
3):1859–1865.
14. Philipp-Dormston W.G., Hilton S., Nathan M., et al. Global approaches to the
prevention and management of delayed-onset adverse reactions with hyaluronic
acid fillers. Plast Reconstr Surg. 2020;145(4):929–939.
15. Makrantonaki E., Zouboulis C.C. The skin as an endocrine
organ. Dermatoendocrinol. 2011;3(1):1–11.
16. Rosenfield R.L. Hyperandrogenism in women: pathophysiology and clinical
relevance. Endocr Rev. 2020;41(5):671–715.
17. Barber T.M., Franks S. Obesity and polycystic ovary syndrome. Clin Endocrinol
(Oxf). 2021;95(4):531–541.
18. Kim E.J., Lee J.H., Kim Y.J., et al. Influence of hormonal fluctuations on skin
biophysical properties in women of reproductive age. Int J
Dermatol. 2021;60(9):1110–1117.