SYNTHESIS, MOLECULAR AND CRYSTAL STRUCTURE, AND BIOLOGICAL ACTIVITY OF A NEW METAL COMPLEX DERIVED FROM 4-AMINOBENZOIC ACID
Keywords:
Keywords: 4-Aminobenzoic acid, Zn(II) complex, crystal structure, supramolecular interactions, antibacterial activity, antioxidant.Abstract
Abstract. A novel zinc(II) complex derived from 4-aminobenzoic acid (PABA)
was synthesized using ZnCl₂ as the metal precursor. The complex was characterized by
elemental analysis, FTIR, UV–Vis, NMR, thermal gravimetric analysis (TGA), and
single-crystal X-ray diffraction (SCXRD). Spectral and structural data confirmed the
bidentate coordination of the ligand through the carboxylate oxygen and amino
nitrogen atoms, forming a distorted octahedral geometry around the Zn(II) center. The
crystal packing was stabilized by an extensive network of intermolecular hydrogen
bonds and π–π stacking interactions.
The thermal analysis revealed high stability of the complex up to 300 °C, while
biological screening demonstrated significant antibacterial and antioxidant activity
compared to the free ligand. The results suggest that the synthesized Zn(II) complex
can serve as a promising multifunctional compound for bioinorganic and
pharmaceutical applications.
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