QANDLI DIABETNI DAVOLASHNING ZAMONAVIY USULLARI
Keywords:
KALIT SO‘ZLAR: Qandli diabet, insulin terapiyasi, insulin analoglari, GLP-1 agonistlari, SGLT-2 ingibitorlari, insulin nasosi, uzluksiz glyukoza monitoringi, sun’iy me’da osti bezi, bariatrik jarrohlik, gen terapiyasi.Abstract
Ushbu maqolada XXI asrning eng keng tarqalgan surunkali kasalliklaridan biri
— qandli diabet va uni davolashning zamonaviy usullari ilmiy nuqtai nazardan keng
yoritiladi. Qandli diabet — me’da osti bezi tomonidan ishlab chiqariladigan insulin
gormoni yetishmovchiligi yoki to‘qimalarning unga sezgirligini yo‘qotishi natijasida
yuzaga keladigan endokrin kasallikdir. Maqolada 1- va 2-tipdagi diabetning
patogenetik xususiyatlari, klinik manzarasi va zamonaviy davolash strategiyalari
batafsil tahlil qilinadi.
Shuningdek, davolashning yangi farmakologik vositalari — insulin analoglari,
GLP-1 retseptor agonistlari, SGLT-2 ingibitorlari, DPP-4 ingibitorlari — bilan bir
qatorda zamonaviy texnologiyalar, ya’ni insulin nasoslari, uzluksiz glyukoza
monitoringi, “sun’iy me’da osti bezi” tizimlari, bariatrik jarrohlik va Langergans
orolchalari transplantatsiyasi kabi usullar muhokama qilinadi. Tadqiqot natijalari
individual yondashuv va zamonaviy texnologiyalarni qo‘llash diabet asoratlarini
sezilarli darajada kamaytirish va bemorlar hayot sifatini oshirish imkonini berishini
ko‘rsatadi.
References
FOYDALANILGAN ADABIYOTLAR
– Ismailov, S. I., & Tashmanova, A. B. (2022). Endokrinologiya va qandli diabet.
— Toshkent: Tibbiyot nashriyoti.
– American Diabetes Association (ADA). (2024). Standards of Medical Care in
Diabetes — Diabetes Care, Vol. 47, Suppl. 1.
– International Diabetes Federation (IDF). (2024). IDF Diabetes Atlas, 11th
edition. — Brussels: IDF.
– Powers, A. C., et al. (2023). Type 1 Diabetes Mellitus: Much Progress, Many
Opportunities. Journal of Clinical Investigation, 133(2).
– Davies, M. J., et al. (2022). Management of hyperglycaemia in type 2 diabetes
— ADA/EASD consensus report. Diabetologia, 65, 1925–1966.
– World Health Organization (WHO). (2023). Global report on diabetes —
Prevention and management strategies.
– Rahimov, X. (2021). Klinik endokrinologiya asoslari. — Toshkent: Yangi asr
avlodi.
– Vertex Pharmaceuticals. (2024). VX-880 clinical trial results for type 1 diabetes
— Press release and scientific summary.
